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Reduce: Development of methods for the reduction of laboratory animal numbers

In the following you will find current research projects of the Bf3R, which are dedicated to the reduction of laboratory animal numbers.


Das Bundesinstitut für Risikobewertung

Biometric Methods

The reproducibility of animal test results, especially in basic biomedical research, has been repeatedly questioned scientifically in the past and led to the "reducibility crisis". The Bf3R wants to find out which methodological and institutional changes in research and the publication process lead to the reduction of unnecessary experiments. This work includes the development of mathematical models.

Classification of the Non-technical Project Summaries with ICD Codes

The Bf3R systematically evaluates approved applications to conduct animal experiments in order to specifically identify the research fields for which a constant number of animal experiments are approved. In these areas, the development of alternative methods as well as measures to reduce animal numbers and improve the welfare of laboratory animals is particularly useful, as many animals would benefit.


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