Abgeschlossene Projekte

Funding by: German Research Foundation (DFG)

Funding period: 2017 - 2021

Aim: Assessing the burden of mice in animal experiments is a complex undertaking from both ethical and biomedical perspectives. The methods used in this project allow for burden analysis from the animals' perspective by incorporating expectancy valence and preferences.

3R Relevance: A standardized stress classification according to measurable and clearly defined criteria helps to minimize pain and suffering of laboratory animals in terms of the Animal Welfare Act.

Publications:

Habedank A., Kahnau Pshort forphosphorus., Diederich K., Lewejohann L. (2018) Severity assessment from an animal's point of view. Berliner und Münchener Tierärztliche Wochenschrift 2018:18007.

Lewejohann L., Schwabe K., Häger C., Jirkof Pshort forphosphorus. (2020) Impulse for animal welfare outside the experiment. Lab Anim.; 54(2):150-158. doi: External Link:10.1177/0023677219891754.

Lewejohann, L. (2020): Enrichment für Versuchstiere. LBH: 10. Leipziger Tierärztekongress – Tagungsband 1, 452-454.

Weegh N., Füner J., Janke Oshort foroxygen., Winter Y., Jung C., Struve B, Wassermann L, Lewejohann L, Bleich A, Häger C. (2020) Wheel running behaviour in group-housed female mice indicates disturbed wellbeing due to DSS colitis. Lab Anim.; 54(1):63-72. doi: External Link:10.1177/0023677219879455.

Leenaars, C.H.C., van der Mierden, S., Durst, M., Goerlich-Jansson, V.C., Ripoli, F.L., Keubler, L.M., Talbot, S.R., Boyle, E., Habedank, A., Jirkof, Pshort forphosphorus., Lewejohann, L., Gass, Pshort forphosphorus., Tolba, R., Bleich, A. (2020) Measurement of corticosterone in mice: a protocol for a mapping review. Lab Anim.; 54(1):26-32. doi: External Link:10.1177/0023677219868499.

Jirkof, Pshort forphosphorus., Rudeck, J., Lewejohann, L. (2019) Assessing Affective State in Laboratory Rodents to Promote Animal Welfare-What Is the Progress in Applied Refinement Research? Animals (Basel); 9(12):1026. doi: External Link:10.3390/ani9121026.

Kahnau, Pshort forphosphorus., Habedank, A., Diederich, K., Lewejohann, L. (2020) Behavioral Methods for Severity Assessment. Animals (Basel); 10(7):1136. doi: External Link:10.3390/ani10071136.

Van der Mierden, S., Leenaars, C.H.C., Boyle, E.C., Ripoli, F.L., Gass, Pshort forphosphorus., Durst, M., Goerlich-Jansson, V.C., Jirkof, Pshort forphosphorus., Keubler, L.M., Talbot, S.R., Habedank, A., Lewejohann, L., Tolba, R.H., Bleich, A. (2021) Measuring endogenous corticosterone in laboratory mice - a mapping review, meta-analysis, and open source database. ALTEX; 38(1):111-122. doi: External Link:10.14573/altex.2004221.

Habedank, A., Kahnau, Pshort forphosphorus., Lewejohann, L. (2021) Alternate without alternative: Neither preference nor learning explains behaviour of C57BL/6J mice in the T-maze. Behaviour; 158(7):625–662. doi: External Link:10.1163/1568539X-bja10085

Habedank, A., Urmersbach, B., Kahnau, Pshort forphosphorus., Lewejohann, L. (2022) Oshort foroxygen mouse, where art thou? The Mouse Position Surveillance System (MoPSS)-an RFID-based tracking system. Behav Res Methods; 54(2):676-689. doi: External Link:10.3758/s13428-021-01593-7.