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Topics in focus

Here we offer an overview of selected articles from the science magazine BfR2GO on the subject of the protection of laboratory animals. Semi-annually the magazine provides information on new developments in evaluation and research in consumer health protection in a compact and comprehensible form.

All articles and issues are available here.

BfR2GO Articles for Bf3R

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BfR2GO 2/2023

Understanding the beginning

Tissue cultures intended to ?simulate? pregnancy and enable testing of potentially risky chemicals ? without animal experiments.

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BfR2GO 1/2023

Even the surplus animals count

Most laboratory animals are not used in experiments at all. What can be done to reduce their number?

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BfR2GO 1/2022

Aberrant mitosis

Centrosomes direct cell division and ensure that each cell carries the same genetic material. Hormones or hormone-like substances can disrupt this process ? thus promoting cancer.

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BfR2GO 1/2022

Where it counts

The German Federal Institute for Risk Assessment (BfR) has been publishing the annual laboratory animal statistics since 2021.

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BfR2GO 2/2021

Mouse welfare principle

Over 60 years ago, two British researchers drew up basic principles for working with laboratory animals. Their thinking has now become a key concept of research in the form of the ?3Rs principles?.

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BfR2GO 2/2021

Interview with Dr. Bettina Bert

Putting the animal first: private lecturer Dr. Bettina Bert on the legal changes governing the approval of experiments.

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BfR2GO 1/2021

Miniature bones

Dr. Frank Schulze grows bone-forming cells on plastic chips. These ?organoids?, which are only a few millimetres in size, can help replace animal experiments.

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BfR2GO 2/2020

Revealing bubbles

Hormones are essential, actually. But an excess can be harmful. BfR scientist Dr. Sebastian Dunst and his team have developed an animal-free test method that can detect the undesired hormonal effects of chemicals.

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BfR2GO 2/2020

Tinkering mice

How clever are rodents? Knowing the answer can also improve the welfare of laboratory animals.

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BfR2GO 1/2020

Rhythmic detoxification

For cells to function properly: the German Centre for the Protection of Laboratory Animals at the BfR is investigating how the internal clock can be used to replace animal experiments.

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BfR2GO 1/2020

When in doubt, for the fish

Research for animal welfare: biologist Dr. Nils Ohnesorge is investigating how zebrafish embryos react to unpleasant stimuli.

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BfR2GO 2/2019

Insights into the worm

The roundworm C. elegans is transparent and tiny. In the wild, it lives in compost. In the laboratory, it might help to replace elaborate animal experiments.

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BfR2GO 2/2019

Better for man and mouse

The Animal Study Registry is intended to make science more transparent and to increase the protection of laboratory animals Over 60 years ago, two British researchers drew up basic principles for working with laboratory animals. Their thinking has now become a key concept of research in the form of the ?3Rs principles?.

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BfR2GO 1/2019

Understanding Mice

Professor Dr. Lars Lewejohann erforscht am BfR das Verhalten von Versuchstieren. Sein Ziel sind bessere Lebensbedingungen fr die Tiere ? und zugleich besProfessor Dr. Lars Lewejohann conducts research into the behaviour of laboratory animals at the BfR. His goal is better living conditions for the animals ? and better science at the same time. Wissenschaft.

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BfR2GO 1/2019

Quick advice for animal welfare

A large group of experts supports the National Committee

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BfR2GO 2/2018

Less suffering ? for humans and animals

The BfR research funding programme supports external projects focusing on the development of innovative alternative methods to animal experiments. Eight projects received funding approval in 2017.

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BfR2GO 2/2018

Hormone traces in the nano-world

Scientists at the BfR are using high-resolution microscopes to examine how oestrogen-like substances alter the body?s cells. This research also serves to replace animal experiments.

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BfR2GO 2/2018

Strict review process

How an animal experiment is authorised

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