Kontakt
12277 Berlin
Deutschland Postanschrift: Bundesinstitut für Risikobewertung
Max-Dohrn-Str. 8-10
Berlin 10589
Deutschland Telephone: 030-18412-29001 030-18412-29001 E-mail: bf3r@bfr.bund.de
Die Wissenschaftlerinnen und Wissenschaftler des Deutschen Zentrums zum Schutz von Versuchstieren (Bf3R) veröffentlichen regelmäßig die Ergebnisse ihrer wissenschaftlichen Arbeit als Artikel in Fachzeitschriften bzw. auf Dokumentenservern für Preprints, in Form von Konferenzpublikationen, als Buchkapitel und Patente.
Hier finden Sie eine nach Erscheinungsjahren geordnete Auflistung aktueller Publikationen des Bf3R seit 2015:
von Coburg, E., Wedler, M., Muino, J.M. et al.kurz füret alii (lat. "und andere") Cell Painting PLUS: expanding the multiplexing capacity of Cell Painting-based phenotypic profiling using iterative staining-elution cycles. Nat Commun 16, 3857 (2025). Externer Link:https://doi.org/10.1038/s41467-025-58765-8
Berrio Sanchez, J. B., Wilzopolski, J., Hohlbaum, K., Kalliokoski, Okurz fürSauerstoff. (2025) The threshold for intracranial self-stimulation does not increase in rats exposed to chronic unpredictable stress – A systematic review and meta-analysis. Behavioural Brain Research, Volume 484, 27 April 2025, 115483
Externer Link:https://doi.org/10.1016/j.bbr.2025.115483
Knetzger, N., Ertych, N., Burgdorf, T., Beranek, J., Oelgeschläger, M., Wächter, J., Horchler, A., Gier, S., Windbergs, M., Fayyaz, S., Grimm, F. A., Wiora, G., Lotz, C. (2025) Non-invasive in vitro NAM for the detection of reversible and irreversible eye damage after chemical exposure for GHS classification purposes (ImAi). Archives of Toxicology 2025 Mar;99(3):1011-1028.
Externer Link:https://doi.org/10.1007/s00204-024-03940-x
Atter, A., Ofori, H., Akonor, Pkurz fürPhosphor. T., Andoh-Odoom, A., Ampah, J., Owusu, M., Peget, F., Overå, R., Kolding, J., Pucher, J. and Kjellevold, M. (2024). Enriched local convenience foods with two different small pelagic fish species increases the nutritional value without compromising taste. International Journal of Gastronomy and Food Science 37(-):100956.
Externer Link:http://dx.doi.org/https://doi.org/10.1016/j.ijgfs.2024.100956
Becker, Pkurz fürPhosphor. C., Güth-Steffens, M., Lazarow, K., Sonntag, N., Braun, D., Masfaka, I., Renko, K., Schomburg, L., Köhrle, J., von Kries, J. Pkurz fürPhosphor., Schweizer, U., Krause, G., Protze, Pkurz fürPhosphor. (2024). Identification of Human TRIAC Transmembrane Transporters. Thyroid 34(7):920-930
Externer Link:https://doi.org/10.1089/thy.2023.0592
Bredow, C., Thery, F., Wirth, E. K., Kespohl, M., Kleinau, G., Kelm, N., Gimber, N., Schmoranzer, J., Voss, M., Klingel, K., Spranger, J., Renko, K., Ralser, M., Mülleder, M., Heuser, A., Knobeloch, K.-Pkurz fürPhosphor., Scheerer, Pkurz fürPhosphor., Kirwan, J., Brüning, U., Berndt, N., Impens, F. and Beling, A. (2024). ISG15 blocks cardiac glycolysis and ensures sufficient mitochondrial energy production during Coxsackievirus B3 infection. Cardiovascular Research.
Externer Link:http://dx.doi.org/10.1093/cvr/cvae026
Butzke, D., Bert, B., Gulich, K., Schönfelder, G. and Neves, M. (preprint). SMAFIRA: a literature-based web tool to assist researchers with retrieval of 3R-relevant information. Laboratory Animals.
Externer Link:http://dx.doi.org/10.1177/00236772241237608
Canbolat, Pkurz fürPhosphor., Wilzopolski, J., Kaessmeyer, S., Filor, V., Vidak, J., Rüger, M., Mägert, H.-J., Forssmann, W.-G. and Bäumer, W. (2024). LEKTI domain 6 displays anti-inflammatory action in vitro and in a murine atopic dermatitis model. Journal of Dermatological Science 115(1):13-20.
Externer Link:http://dx.doi.org/10.1016/j.jdermsci.2024.03.004
Diederich, K., Steinfath, M., Bannach-Brown, A., Bert, B., Butzke, D., Wildner, Pkurz fürPhosphor. L., Wurm, M., Schadock, I. and Heinl, C. (2024). Protocol for the systematic review of age and sex in preclinical models of age-correlated diseases. F1000Research 13(-)
Externer Link:https://doi.org/10.12688/f1000research.153466.1
Drude, N., Nagel-Riedasch, S., Rosshart, S. Pkurz fürPhosphor., Diefenbach, A., Diederich, K., Duerr, C. U., Harms, C., Heppner, F., Kolesnichenko, M., Lewejohann, L., Mall, M. A., Müller, D., Opitz, B., Rosshart, S. Pkurz fürPhosphor., Schönfelder, G., Tölch, U., Willimsky, G. and Jordan, S. (2024). "A facility for laboratory mice with a natural microbiome at Charité – Universitätsmedizin Berlin". Lab animal : information, ideas, methods and materials for the animal research professional
Externer Link:https://www.nature.com/articles/s41684-024-01474-4
Gerhardt, Pkurz fürPhosphor., Begall, S., Frädrich, C., Renko, K., Heinrich, A., Köhrle, J. and Henning, Y. (2024). Low thyroxine serves as an upstream regulator of ecophysiological adaptations in Ansell’s mole-rats. Frontiers in Endocrinology.
Externer Link:https://doi.org/10.3389/fendo.2024.1329083
Hohlbaum, K., Andresen, N., Mieske, Pkurz fürPhosphor., Kahnau, Pkurz fürPhosphor., Lang, B., Diederich, K., Palme, R., Mundhenk, L., Sprekeler, H., Hellwich, Okurz fürSauerstoff., Thöne-Reineke, C. and Lewejohann, L. (2024). Lockbox enrichment facilitates manipulative and cognitive activities for mice [version 2; peer review: 2 approved]. Open Research Europe 4(-):108
Externer Link:https://doi.org/10.12688/openreseurope.17624.2
Hohlbaum, K., Merle, R., Warnke, R., Nagel-Riedasch, S., Thöne-Reineke, C. and Ullmann, K. (online first 2023). The implementation of tunnel handling in a mouse breeding facility revealed strain-specific behavioural responses. Laboratory Animals 0(0):1-13
Externer Link:https://doi.org/10.1177/00236772231215077
Jo, S., Park, S. B., Kim, H., Im, I., Noh, H., Kim, E.-M., Kim, K. Y., Oelgeschlaeger, M., Kim, J.-H. and Park, H.-J. (2024). hiPSC-derived macrophages improve drug sensitivity and selectivity in a macrophage-incorporating organoid culture model. Biofabrication.
Externer Link:http://dx.doi.org/10.1088/1758-5090/ad4c0a
Kadic, A., Oles, Pkurz fürPhosphor., Fischer, B. C., Reetz, A. E., Sylla, B.S., Feiertag, K., Ritz, V., Heise, T., Marx-Stölting, Pkurz fürPhosphor., Tralau, T., Renko, K. and Solano, M. d. L. M. (2024). In vitro and in vivo investigation of a thyroid hormone system-specific interaction with triazoles. Scientific Reports.
Externer Link:https://doi.org/10.1038/s41598-024-55019-3
Kim, H., Kim, S. K., Oelgeschläger, M. and Park, H.-J. (2024). Prediction of Acute Hepatotoxicity With Human Pluripotent Stem Cell-Derived Hepatic Organoids. Current Protocols 4(4):e1015.
Externer Link:http://dx.doi.org/10.1002/cpz1.1015
Kitsara, M., Smajlhodži?-Deljo, M., Gurbeta Pokvic, L., Bert, B., Bubalo, N., Erden, S., Franco, N. H., Chirico, G., Gómez Raja, J., Gonzalez-Uarquin, F., Lang, A., Linklater, N., Mojsova, S., Olsson, I. A. S., Sandvig, I., Schaffert, A., Schmit, M., Schober, S., Sevastre, B., Wilflingseder, D., Ahluwalia, A. and Neuhaus, W. (2024). Introduction of the COST Action IMPROVE on Improving the Quality of Biomedical Science with 3Rs Concepts ATLA (Alternatives to Laboratory Animals) 52(6):326-333
Externer Link:https://doi.org/10.1177/02611929241286024
Lauwereyns, J., Bajramovic, J., Bert, B., Camenzind, S., De Kock, J., Elezovi?, A., Erden, S., Gonzalez-Uarquin, F., Ulman, Y. I., Hoffmann, Okurz fürSauerstoff. I., Kitsara, M., Kostomitsopoulos, N., Neuhaus, W., Petit-Demouliere, B., Pollo, S., Riso, B., Schober, S., Sotiropoulos, A., Thomas, A., Vitale, A., Wilflingseder, D. and Ahluwalia, A. (2024). "Toward a common interpretation of the 3Rs principles in animal research". Lab animal 2024
Externer Link:https://doi.org/10.1038/s41684-024-01476-2
Likurz fürLithium, Y., Deng, D., Höfer, C. T., Kim, J., Heo, W. D., Xu, Q., Liu, X. and Zi, Z. (2024). Liebig’s law of the minimum in the TGF-β/SMAD pathway. Review Commons 20(5):e1012072
Externer Link:https://doi.org/10.1371/journal.pcbi.1012072
Neves, M. (preprint). Detection of fields of applications in biomedical abstracts with the support of argumentation elements. arXiv.
Externer Link:http://dx.doi.org/10.48550/arXiv.2404.06121
Odje, F., Meijer, D., von Coburg, E., van der Hooft, J.J.J., Dunst, S., Medema, M.H. and Volkamer, A. (2024). Unleashing the potential of cell painting assays for compound activities and hazards prediction. Frontiers Toxicology Front. Toxicol. 6:1401036.
Externer Link:https://doi.org/10.3389/ftox.2024.1401036
Ohnesorge, N., Wilzopolski, J., Steinfath, M., Lewejohann, L., Banneke, S., Heinl, C. (Preprint) Assessment of the effect of tricaine (MS-222)-induced anesthesia on brain-wide neuronal activity of zebrafish (Danio rerio) larvae. Front. Neurosci. (2024). Sec. Neuropharmacology, Volume 18 - 2024 |
Externer Link:https://doi.org/10.3389/fnins.2024.1456322
Pont, C., Sampietro, A., Pérez-Areales, F. J., Cristiano, N., Albalat, A., Pérez, B., Bartolini, M., De Simone, A., Andrisano, V., Barenys, M., Teixidó, E., Sabaté, R., Loza, M. I., Brea, J. and Muñoz-Torrero, D. (2024). Stepwise Structural Simplification of the Dihydroxyanthraquinone Moiety of a Multitarget Rhein-Based Anti-Alzheimer Lead to Improve Drug Metabolism and Pharmacokinetic Properties. Pharmaceutics 16(8):982
Externer Link:https://doi.org/10.3390/pharmaceutics16080982
Pederson, C., Vogliano, C., Sadoff, C., D’Cruz, G., Kennedy, G., White, G., Alleway, H., Kim, J. K., Pucher, J., Koome, K., Geagan, K., Chang, K., Mbuya, M., Sumaila, R., Thilsted, S., Palmer, S., Oenema, S., Zimpita, T., Agostini, V. and Battista, W. (2024). Regenerative Aquatic Foods Roadmap.
Externer Link:https://www.aquaculturescience.org/content/dam/tnc/nature/en/documents/RegenerativeAquaticFoodsRoadmap.pdf
Schlegel, L., Kleine, A. S., Doherr, M. G. and Fischer-Tenhagen, C. (2024). How to see stress in chickens: On the way to a Stressed Chicken Scale. Poultry Science 103(8).
Externer Link:http://dx.doi.org/10.1016/j.psj.2024.103875
Wagenaars, F., Cenijn, Pkurz fürPhosphor., Scholze, M., Frädrich, C., Renko, K., Köhrle, J. and Hamers, T. (Online ahead of print). Screening for endocrine disrupting chemicals inhibiting monocarboxylate 8 (MCT8) facilitated thyroid hormone transport using a modified nonradioactive assay. Toxicology in vitro 96.
Externer Link:http://dx.doi.org/10.1016/j.tiv.2023.105770
Wilhelmi, Pkurz fürPhosphor., Haake, V., Zickgraf, F. M., Giri, V., Ternes, Pkurz fürPhosphor., Driemert, Pkurz fürPhosphor., Nöth, J., Scholz, S., Barenys Espadaler, M., Flick, B., Birk, B., Kamp, H., Landsiedel, R. and Funk-Weyer, D. (2024). Molecular signatures of angiogenesis inhibitors: a single-embryo untargeted metabolomics approach in zebrafish. Archives of Toxicology 98(-):943-956
Externer Link:https://doi.org/10.1007/s00204-023-03655-5
Vogliano, C., Kennedy, G., Alleway, H., Sadoff, C., D’Cruz, G., White, G., Kim, J. K., Pucher, J., Koome, K., Geagan, K., Chang, K., Mbuya, M., Thilsted, S., Palmer, S., Sumaila, U. R. and Battista, W. (2024). Regenerative aquatic foods can be a win-win for human and planetary health. Nature Food 5(-):718–719
Externer Link:https://doi.org/10.1038/s43016-024-01043-5
Audebert, M., Assmann, A.-S., Azqueta, A., Babica, Pkurz fürPhosphor., Benfenati, E., Bortoli, S., Bouwman, Pkurz fürPhosphor., Braeuning, A., Burgdorf, T., Coumoul, X., Debizet, K., Dusinska, M., Ertych, N., Fahrer, J., Fetz, V., Le Hegarat, L., Lopez de Cerain, A., Heusinkveld, H. J., Hogeveen, K., Jacobs, M. N., Luijten, M., Raitano, G., Recoules, C., Runden-Pran, E., Saleh, M., Sovadinova, I., Stampar, M., Thibol, L., Tomkiewicz, C., Vettorazzi, A., Van de Water, B., El Yamani, N., Zegura, B. and Oelgeschläger, M. (2023). New approach methodologies to facilitate and improve the hazard assessment of non-genotoxic carcinogens-a PARC project. Frontiers in Toxicology 5:1220998. Externer Link:http://dx.doi.org/10.3389/ftox.2023.1220998
Brandwein, C., Leenaars, C. H. C., Becker, L., Pfeiffer, N., Iorgu, A.-M., Hahn, M., Vairani, G. A., Lewejohann, L., Bleich, A., Mallien, A. S. and Gass, Pkurz fürPhosphor. (2023). A systematic mapping review of the evolution of the rat Forced Swim Test: Protocols and outcome parameters. Pharmacological Research 196:106917. Externer Link:http://dx.doi.org/10.1016/j.phrs.2023.106917
Dolokov, A., Andersen, N., Hohlbaum, K., Thöne-Reineke, C., Lewejohann, L., Hellwich, Okurz fürSauerstoff. (2023) Upper bound tracker: a multi-animal tracking solution for closed laboratory settings. Scitepress, 4, 945–952. Externer Link:https://dx.doi.org/10.5220/0011609500003417
Engel, A. M., El-Khatib, A. H., Klevenhusen, F., Weiss, M., Aboling, S., Sachse, B., Schäfer, B., Weigel, S., Pieper, R. and Fischer-Tenhagen, C. (2023). Detection of Hypoglycin A and MCPrG Metabolites in the Milk and Urine of Pasture Dairy Cows after Intake of Sycamore Seedlings. Journal of agricultural and food chemistry 71:10751-10760. Externer Link:http://dx.doi.org/https://doi.org/10.1021/acs.jafc.3c01248
Fischer-Tenhagen, C., Bohm, D., Finnah, A., Arlt, S., Schlesinger, S., Borchardt, S., Sutter, F., Tippenhauer, C. M., Heuwieser, W. and Venjakob, Pkurz fürPhosphor. L. (2023). Residue Concentrations of Cloxacillin in Milk after Intramammary Dry Cow Treatment Considering Dry Period Length. Animals 13(16):2558. Externer Link:http://dx.doi.org/https://doi.org/10.3390/ani13162558
GarridoGamarro, E., Svanevik, C. S., Lundebye, A.-K., Sanden, M., D’Agostino, E., Kjellevold, M., Pincus, L. and Pucher, J. (2023). Challenges in the Implementation of Food Safety and Quality Assurance Systems in Small-Scale Fisheries. Food Quality and Safety, 7, 1-9. Externer Link:http://dx.doi.org/10.1093/fqsafe/fyad007
Gerhardt, Pkurz fürPhosphor., Begall, S., Frädrich, C., Renko, K., Hildebrandt, T. B., Holtze, S., Heinrich, A., Sahm, A., Meci, X., Köhrle, J., Rijntjes, E. and Henning, Y. (2023). Comparative analysis of thyroid hormone systems in rodents with subterranean lifestyle. Scientific Reports 13, 3122. Externer Link:http://dx.doi.org/10.1038/s41598-023-30179-w
Hackler, J., Demircan, K., Chillon, T. S., Sun, Q., Geisler, N., Schupp, M., Renko, K., Schomburg, L. (2023) High throughput drug screening identifies resveratrol as suppressor of hepatic SELENOP expression. Redox Biology, 2023 Feb; 59: 102592. Externer Link:https://doi.org/10.1016/j.redox.2022.102592
Hobbiesiefken, U., Urmersbach, B., Jaap, A., Diederich, K. and Lewejohann, L. (2023). Rating enrichment items by female group-housed laboratory mice in multiple binary choice tests using an RFID-based tracking system. PLoS One 18 (1), e0278709. Externer Link:http://dx.doi.org/10.1371/journal.pone.0278709
Kahnau, Pkurz fürPhosphor., Jaap, A., Diederich, K., Gygax, L., Rudeck, J. and Lewejohann, L. (2023). Determining the value of preferred goods based on consumer demand in a home-cage based test for mice. Behavior Research Methods 55 (2), 751-766. Externer Link:http://dx.doi.org/10.3758/s13428-022-01813-8
Kahnau, Pkurz fürPhosphor., Jaap, A., Urmersbach, B., Diederich, K. and Lewejohann, L. (2022). Development of an IntelliCage-based cognitive bias test for mice. Open Research Europe. Externer Link:http://dx.doi.org/https://doi.org/10.12688/openreseurope.15294.1
Kahnau, Pkurz fürPhosphor., Mieske, Pkurz fürPhosphor., Wilzopolski, J., Kalliokoski, Okurz fürSauerstoff., Mandillo, S., Hölter, Sabine M., Voikar, V., Amfim, A., Badurek, S., Bartelik, A., Caruso, A., ?ater, M., Ey, E., Golini, E., Jaap, A., Hrncic, D., Kiryk, A., Lang, B., Loncarevic?Vasiljkovic, N., Meziane, H., Radzevi?ien?, A., Rivalan, M., Scattoni, M. L., Torquet, N., Trifkovic, J., Ulfhake, B., Thöne?Reineke, C., Diederich, K., Lewejohann, L. and Hohlbaum, K. (2023). A systematic review of the development and application of home cage monitoring in laboratory mice and rats. BMC Biology 21. Externer Link:http://dx.doi.org/https://doi.org/10.1186/s12915-023-01751-7
Knipper, A.-D., Göhlich, S., Stingl, K., Ghoreishi, N., Fischer-Tenhagen, C., Bandick, N., Tenhagen, B.-A. and Crease, T. (2023). Longitudinal Study for the Detection and Quantification of Campylobacter spp. in Dairy Cows during Milking and in the Dairy Farm Environment. Foods 12(8). Externer Link:http://dx.doi.org/https://doi.org/10.3390/foods12081639
Koch, F., Pieper, R. and Fischer-Tenhagen, C. (2023). Messung der Körpertemperatur beim Schwein: Können Infrarotthermometer eine Alternative sein?. Tierärztliche Praxis: Ausgabe Großtiere / Nutztiere 51(02):84-92. Externer Link:http://dx.doi.org/10.1055/a-2046-5061
Körber, N. (2023) MIA is an open-source standalone deep learning application for microscopic image analysis. Cell Reports Methods, 26 June 2023. Externer Link:https://doi.org/10.1016/j.crmeth.2023.100517
Kühne, B. A., Gutierrez-Vázquez, L., Sánchez Lamelas, E., Guardia-Escote, L., Pla, L., Loreiro, C., VGratacós, E., Barenys, M. and Illa, M. (2023). Lactoferrin/sialic acid prevents adverse effects of intrauterine growth restriction on neurite length: investigations in an in vitro rabbit neurosphere model. Frontiers in Celular Neuroscience 17. Externer Link:http://dx.doi.org/https://doi.org/10.3389/fncel.2023.1116405
Lang, B., Kahnau, Pkurz fürPhosphor., Hohlbaum , K., Mieske, Pkurz fürPhosphor., Andresen, N. Pkurz fürPhosphor., Boon, M. N., Thöne-Reineke, C., Lewejohann, L. and Diederich, K. (2023). Challenges and advanced concepts for the assessment of learning and memory function in mice. Frontiers in Behavioral Neuroscience 17:1230082. Externer Link:http://dx.doi.org/https://doi.org/10.3389/fnbeh.2023.1230082
Mee, J. F., Szenci, Okurz fürSauerstoff. and Fischer-Tenhagen, C. (Online ahead of print). Academics meet practitioners: Interactive exchange instead of consuming knowledge on dairy calving management. Reproduction in Domestic Animals. Externer Link:https://doi.org/10.1111/rda.14507
Mieske, Pkurz fürPhosphor., Scheinpflug, J., Yorgan, T. A., Brylka, L., Palme, R., Hobbiesiefken, U., Preikschat, J., Lewejohann, L. and Diederich, K. (2023). Effects of more natural housing conditions on the muscular and skeletal characteristics of female C57BL/6J mice. Laboratory Animal Research 39:9. Externer Link:http://dx.doi.org/10.1186/s42826-023-00160-9
Mills, D. J., Simmance, F., Byrd, K., Ahern, M., Cohen, Pkurz fürPhosphor., D’Agostino, E., Fiorella, K., Garrido-Gamarro., E., Gondwe, E., Hicks, C., Kaunda, E., Kjellevold, M., Kolding, J., Levsen, A., Lundebye, A. K., Marinda, Pkurz fürPhosphor., McNeil, A., Nagoli, J., Nankwenya, B., Nico, G., O’Meara, L., Pincus, L., Pucher, J., J., R., Roscher, M., Sanden, M., Seow, T. K., Svanevik, C., Teoh, S. J., Thilsted, S., Tilley, A. and Tuazon, M. A. (2023). Contributions of small-scale fisheries to food security and nutrition. Illuminating Hidden Harvests. 145-174. Externer Link:https://www.fao.org/3/cc4576en/cc4576en.pdf
Neves, M., Klippert, A., Knöspel, F., Rudeck, J., Stolz, A., Ban, Z., Becker, M., Diederich, K., Grune, B., Kahnau, Pkurz fürPhosphor., Ohnesorge, N., Pucher, J., Schönfelder, G., Bert, B. and Butzke, D. (2023). Automatic classification of experimental models in biomedical literature to support searching for alternative methods to animal experiments. Journal of Biomedical Semantics 14(13). Externer Link:http://dx.doi.org/https://doi.org/10.1186/s13326-023-00292-w
Ramhoj, L., Axelstad, M., Baert, Y., Canas-Portilla, A., Chalmel, F., Dahmen, L., de la Vieja, A., Evrard, B., Haigis, A.C., Hamers, T., Heikamp, K., Holbech, H., Iglesias-Hernandez, Pkurz fürPhosphor., Knapen, D., Marchandise, L., Morthorst, J.E., Nikolov, N.G., Nissen, A.C.V.E., Oelgeschlaeger, M., Renko, K., Rogiers, V., Schüürmann, G., Stinckens, E., Stub, M.H., Torres-Ruiz, M., Van Duursen, M., Vanhaecke, T., Vergauwen, L., Wedebye, E.B., Svingen, T. (2023) New approach methods to improve human health risk assessment of thyroid hormone system disruption–a PARC project. Frontiers Toxicology, 17 May 2023.
Externer Link:https://doi.org/10.3389/ftox.2023.1189303
Romero, N. G., Gutierrez, G., Teixido, E., Likurz fürLithium, L., Klose, J., Leung, Pkurz fürPhosphor. C., Cañigueral, S., Fritsche, E. and Barenys, M. (2023). Developmental neurotoxicity evaluation of three Chinese herbal medicines in zebrafish larvae by means of two behavioral assays: touch-evoked response and light/dark transition. Reproductive Toxicology 121:108469. Externer Link:http://dx.doi.org/https://doi.org/10.1016/j.reprotox.2023.108469
SCHEER (Scientific Committee on Health, Environmental and Emerging Risks), Opinion on the Revision of Annexes III and IV of Directive 2010/63/EU on the protection of animals used for scientific purposes regarding accommodation parameters and methods of killing for zebrafish, and accommodation parameters for Passerine birds, adopted on 25 September 2023
Externer Link:https://health.ec.europa.eu/publications/scheer-revision-annexes-iii-and-iv-directive-201063eu-protection-animals-used-scientific-purposes_en
Scheinpflug, J., Höfer, C. T., Schmerbeck, S. S., Steinfath, M., Doka, J., Afework Tesfahunegn, Y., Violet, N., Renko, K., Gulich, K., John, T., Schneider, M. R., Wistorf, E., Schönfelder, G., Schulze, F. (2023) A microphysiological system for studying human bone biology under simultaneous control of oxygen tension and mechanical loading. Lab on a Chip, 2023 July 3. Externer Link:https://doi.org/10.1039/D3LC00154G
Teixidó, E., Riera-Colomer, C., Raldúa, D., Pubill, D., Escubedo, E., Barenys, M. and López-Arnau, R. (2023). First generation synthetic cathinones produce arrhythmia in zebrafish eleutheroembryos. A New Approach Methodology for New Psychoactive Substances cardiotoxicity evaluation. International Journal of Molecular Sciences. Externer Link:http://dx.doi.org/https://doi.org/10.3390/ijms241813869
Uluckan, Ö., Bruno, S., Wang, Y., Wack, N., Wilzopolski, J., Goetschy, J.-F., Delucis-Bronn, C., Urban, B., Fehlmann, D., Stark, H., Hauchard, A., Roussel, E., Kempf, D., Kaupmann, K., Raulf, F., Bäumer, W., Röhn, T. A. and Zerwes, H. G. (2023). Adriforant is a functional antagonist of histamine receptor 4 and attenuates itch and skin inflammation in mice. European Journal of Pharmacology 945, 175533. Externer Link:http://dx.doi.org/10.1016/j.ejphar.2023.175533
Wagenknecht, T., Eusemann, B., Schwedhelm, Pkurz fürPhosphor., Schönfelder, G. and Bert, B. (2023). Das Vorliegen eines “vernünftigen Grundes” bei der Tötung überzähliger Versuchstiere. Natur und Recht 45, 225–233. Externer Link:https://doi.org/10.1007/s10357-022-4103-8
Wagenknecht, T., Eusemann, B., Schwedhelm, Pkurz fürPhosphor., Schönfelder, G., Bert, B. (2023) Die Tötung überzähliger Versuchstiere – das Erfordernis des „vernünftigen Grundes“ und die Übertragung aktueller Rechtsprechung auf den Versuchstierbereich. Natur und Recht, Januar 2023, 45, 22-30, Externer Link:https://doi.org/10.1007/s10357-022-4102-9
Weber, A.G., Birk, B., Giri, V., Hoffmann, S., Renko, K., Coecke, S., Schneider, S., Funk-Weyer, D., and Landsiedel, R. (2023) Assessment of the Predictivity of DIO1-SK Assay to Investigate DIO1 Inhibition in Human Liver Microsomes. Applied In Vitro Toxicology, Vol. 9, No. 2, 15 June 2023.
Externer Link:https://doi.org/10.1089/aivt.2022.0016
Wessels, L., Kjellevold, M., Kolding, J., Odoli, C., Aakre, I., Reich, F. and Pucher, J. (2023). Putting small fish on the table: The underutilized potential of small indigenous fish to improve food and nutrition security in East Africa. Food Security. Externer Link:http://dx.doi.org/https://doi.org/10.1007/s12571-023-01362-8
Wewetzer, H., Wagenknecht, T., Bert, B. and Schönfelder, G. (2023). The fate of surplus laboratory animals. EMBO Reports 24, :e56551. Externer Link:http://dx.doi.org/10.15252/embr.202256551
Wilhelmi, Pkurz fürPhosphor., Giri, V., Zickgraf, F. M., Haake, V., Henkes, S., Driemert, Pkurz fürPhosphor., Michaelis, Pkurz fürPhosphor., Busch, W., Scholz, S., Flick, B., Barenys, M., Birk, B., Kamp, H., Landsiedel, R. and Funk-Weyer, D. (2023). A metabolomics approach to reveal the mechanism of developmental toxicity in zebrafish embryos exposed to 6-propyl-2-thiouracil. Chemico-Biological Interactions 382. Externer Link:http://dx.doi.org/https://doi.org/10.1016/j.cbi.2023.110565
Wilzopolski, J., Putrianti, E., Balik, Pkurz fürPhosphor., Goerlich, S., Lindner, T. and Ohnesorge, N. (2023). Assessment of the antinociceptive efficacy of analgesics, anesthetics and other compounds in zebrafish (Danio rerio). Journal of Veterinary Pharmacology and Therapeutics 46(S1):45-45. Externer Link:http://dx.doi.org/10.1111/jvp.13202
Wolter, A., Bucher, C. H., Kurmies, S., Schreiner, V., Konietschke, F., Hohlbaum, K., Klopfleisch, R., Löhning, M., Thöne-Reineke, C., Buttgereit, F., Huwyler, J., Jirkof, Pkurz fürPhosphor., Rapp, A. E. and Lang, A. (2023). A buprenorphine depot formulation provides effective sustained post-surgical analgesia for 72 h in mouse femoral fracture models. Scientific Reports 13 (1), 3824. Externer Link:http://dx.doi.org/10.1038/s41598-023-30641-9
Bühler, M., Fahrländer, J., Sauter, A., Becker, M., Wistorf, E., Steinfath, M. and Stolz, A. (2022). GPER1 links estrogens to centrosome amplification and chromosomal instability in human colon cells. Life Science Alliance, 6 (1), e202201499. Externer Link:http://dx.doi.org/10.26508/lsa.202201499
Bühler, M. & Stolz, A. (2022) Estrogens – Origin of Centrosome Defects in Human cancer? Cells, 11(3), 432. Externer Link:https://doi.org/10.3390/cells11030432
Deng, D. & Zi, Z. (2022). Absolute Quantification of TGF-beta Signaling Proteins Using Quantitative Western Blot. In: Z. Zi and X. Liu. TGF-Beta Signaling. Methods and Protocols. Methods in Molecular Biology, 2488. Humana, New York, NY. 1-12. Externer Link:http://dx.doi.org/10.1007/978-1-0716-2277-3_1
Diederich, K., Schmitt, K., Schwedhelm, Pkurz fürPhosphor., Bert, B. and Heinl, C. (2022). A guide to open science practices for animal research. PLOS Biology, 20 (9), e3001810. Externer Link:http://dx.doi.org/10.1371/journal.pbio.3001810
Engel, A. M., Klevenhusen, F., Moenning, J.-L., Numata, J., Fischer-Tenhagen, C., Sachse, B., Scha?fer, B., Fry, H., Kappenstein, Okurz fürSauerstoff. and Pieper, R. (2022). Investigations on the Transfer of Quinolizidine Alkaloids from Lupinus angustifolius into the Milk of Dairy Cows. Journal of Agricultural and Food Chemistry, 70 (37), 11749–11758. Externer Link:http://dx.doi.org/10.1021/acs.jafc.2c02517
Escher, B. I., Lamoree, M., Antignac, J.-Pkurz fürPhosphor., Scholze, M., Herzler, M., Hamers, T., Jensen, T. K., Audebert, M., Busquet, F., Maier, D., Oelgeschläger, M., Valente, M. J., Boye, H., Schmeisser, S., Dervilly, G., Piumatti, M., Motteau, S., König, M., Renko, K., Margalef, M., Cariou, R., Ma, Y., Treschow, A. F., Kortenkamp, A. and Vinggaard, A. M. (2022). Mixture Risk Assessment of Complex Real-Life Mixtures-The PANORAMIX Project. International Journal of Environmental Research and Public Health, 19 (20), 12990. Externer Link:http://dx.doi.org/10.3390/ijerph192012990
Fischer-Tenhagen, C., Meier, J. and Pohl, A. (2022). “Do not look at me like that”: Is the facial expression score reliable and accurate to evaluate pain in large domestic animals? A systematic review. Frontiers in Veterinary Science, 9, 1002681. Externer Link:http://dx.doi.org/10.3389/fvets.2022.1002681
Graffunder, A. S., Paisdzior, S., Opitz, R., Renko, K., Kühnen, Pkurz fürPhosphor. & Biebermann, H. (2022). Design and Characterization of a Fluorescent Reporter Enabling Live-cell Monitoring of MCT8 Expression. Experimental and Clinical Endocrinology & Diabetes, 130 (02), 134-140. Externer Link:http://dx.doi.org/10.1055/a-1522-8535
Habedank, A., Urmersbach, B., Kahnau, Pkurz fürPhosphor. and Lewejohann, L. (2022). Okurz fürSauerstoff mouse, where art thou? The Mouse Position Surveillance System (MoPSS) - an RFID-based tracking system. Behavior Research Methods, 54 (2), 676–689. Externer Link:http://dx.doi.org/10.3758/s13428-021-01593-7
Heinl, C., Schönfelder, G. and Bert, B. (2022). Preregistration in Animal Research. In: J. Faintuch and S. Faintuch Integrity of Scientific Research: Fraud, Misconduct and Fake News in the Academic, Medical and Social Environment. 371-378. Springer. Externer Link:http://dx.doi.org/10.1007/978-3-030-99680-2_37
Heinl, C., Scholman-Végh, A. M. D., Mellor, D., Schönfelder, G., Strech, D., Chamuleau, S. & Bert, B. (2022). Declaration of common standards for the preregistration of animal research – speeding up the scientific progress. PNAS Nexus, pgac016. Externer Link:http://dx.doi.org/10.1093/pnasnexus/pgac016
Jacobs, M. N., Ezendam, J., Hakkert, B., Oelgeschläger, M. & Hakkert, B. (2022). Potential of concentration-response data to broaden regulatory application of in vitro test guidelines. ALTEX - Alternatives to Animal Experimentation. Externer Link:http://dx.doi.org/10.14573/altex.2107091
Kahnau, Pkurz fürPhosphor., Jaap, A., Hobbiesiefken, U., Mieske, Pkurz fürPhosphor., Diederich, K., Thöne-Reineke, C., Lewejohann, L. and Hohlbaum, K. (2022). A preliminary survey on the occurrence of barbering in laboratory mice in Germany. Animal Welfare, 31 (4), 433-436. Externer Link:http://dx.doi.org/10.7120/09627286.31.4.009
Klutzny, S., Kornhuber, M., Morger, A., Schönfelder, G., Volkamer, A., Oelgeschläger, M. & Dunst, S. (2022). Quantitative high-throughput phenotypic screening for environmental estrogens using the E-Morph Screening Assay in combination with in silico predictions. Environment International, 158, 106947. Externer Link:http://dx.doi.org/10.1016/j.envint.2021.106947
Körber, N. (2022). MIA: An Open Source Standalone Deep Learning Application for Microscopic Image Analysis. bioRxiv. Externer Link:http://dx.doi.org/10.1101/2022.01.14.476308
Kohler, J., Mei, J., Banneke, S., Winter, Y., Endres, M. and Emmrich, J. V. (2022). Assessing spatial learning and memory in mice: Classic radial maze versus a new animal-friendly automated radial maze allowing free access and not requiring food deprivation. Frontiers in Behavioral Neuroscience, 16, 1013624. Externer Link:http://dx.doi.org/10.3389/fnbeh.2022.1013624
Kornhuber, M. & Dunst, S. (2022). Automated Classification of Cellular Phenotypes Using Machine Learning in Cellprofiler and CellProfiler Analyst. In: Z. Zi and X. Liu. TGF-Beta Signaling. Methods and Protocols. Methods in Molecular Biology, 2488. Humana, New York, NY. 1-12. Externer Link:http://dx.doi.org/10.1007/978-1-0716-2277-3_14
Likurz fürLithium, Y. & Zi, Z. (2022). Optogenetic Control of TGF-beta Signaling. In: Z. Zi and X. Liu. TGF-Beta Signaling. Methods and Protocols. Methods in Molecular Biology, 2488. Humana, New York, NY. 113-124. Externer Link:http://dx.doi.org/10.1007/978-1-0716-2277-3_9
Mackert, Okurz fürSauerstoff., Wirth, E.K., Sun, R., Winkler, J., Liu, A., Renko, K., Kunz, S., Spranger, J. & Brachs, S. (2022). Impact of metabolic stress induced by diets, aging and fasting on tissue oxygen consumption. Molecular Metabolism, 64: 101563. Externer Link:https://doi.org/10.1016/j.molmet.2022.101563
Mieske, Pkurz fürPhosphor., Hobbiesiefken, U., Fischer-Tenhagen, C., Heinl, C., Hohlbaum, K., Kahnau, Pkurz fürPhosphor., Meier, J., Wilzopolski, J., Butzke, D., Rudeck, J., Lewejohann, L. & Diederich, K. (2022). Bored at home?—A systematic review on the effect of environmental enrichment on the welfare of laboratory rats and mice, Frontiers in Veterinary Science, 9. Externer Link:https://doi.org/10.3389/fvets.2022.899219
Mihelakis, M., Ndikung, J., Oelgeschläger, M. & Ertych, N. (2022). The 4th dimension of in vitro systems - Time to level up. Environment International, 164, 107256. Externer Link:http://dx.doi.org/10.1016/j.envint.2022.107256
Neves, M., Yepes, A. J., Siu, A., Roller, R., Thomas, Pkurz fürPhosphor., Navarro, M. V., Yeganova, L., Wiemann, D., Di Nunzio, G. M., Vezzani, F., Gerardin, C., Bawden, R., Estrada, D. J., Lima-López, S., Farré-Maduell, E., Krallinger, M., Grozea, C. and Névéol, A. (2022). Findings of the WMT 2022 Biomedical Translation Shared Task: Monolingual Clinical Case Reports. Proceedings of the Seventh Conference on Machine Translation (WMT), 694-723.
Niethammer, M., Burgdorf, T., Wistorf, E., Schönfelder, G. and Kleinsorge, M. (2022). In vitro models of human development and their potential application in developmental toxicity testing. Development, 149 (20), dev200933. Externer Link:http://dx.doi.org/10.1242/dev.200933
Renko, K., Kerp, H., Pape, J., Rijntjes, E., Burgdorf, T., Führer, D. & Köhrle, J. (2022). Tentative Application of a Streamlined Protocol to Determine Organ-Specific Regulations of Deiodinase 1 and Dehalogenase Activities as Readouts of the Hypothalamus-Pituitary-Thyroid-Periphery-Axis. Frontiers in Toxicology, 4, 822993. Externer Link:http://dx.doi.org/10.3389/ftox.2022.822993
Tappe-Theodor, A., Pitzer, C., Lewejohann, L., Jirkof, Pkurz fürPhosphor., Siegeler, K., Segelcke, A., Drude, N., Pradier, B., Pogatzki-Zahn, E., Hollinderbaumer, B. & Segelcke, D. (2022). The "WWHow" Concept for Prospective Categorization of Post-operative Severity Assessment in Mice and Rats. Frontiers in Veterinary Science, 9, 841431. Externer Link:http://dx.doi.org/10.3389/fvets.2022.841431
Weber, A. G., Birk, B., Herrmann, C., Huener, H.-A., Renko, K., Coecke, S., Schneider, S., Funk-Weyer, D. and Landsiedel, R. (2022). A New Approach Method to Study Thyroid Hormone Disruption: Optimization and Standardization of an Assay to Assess the Inhibition of DIO1 Enzyme in Human Liver Microsomes. Applied In Vitro Toxicology, 8 (3), 67-82. Externer Link:http://dx.doi.org/10.1089/aivt.2022.0010
Zi, Z. & Liu, X. (2022). TGF-Beta Signaling. Methods in Molecular Biology, 2488. Humana, New York, NY.Externer Link: Externer Link:http://dx.doi.org/10.1007/978-1-0716-2277-3
Accuosto, Pkurz fürPhosphor., Neves, M., & Saggion, H. (2021). Argumentation mining in scientific literature: from computational linguistics to biomedicine. Externer Link:http://repositori.upf.edu/handle/10230/47600
Akonor, Pkurz fürPhosphor. T., Atter, A., Owusu, M., Ampah, J., Andoh?Odoom, A., Overå, R., Kjellevold, M., Pucher, J. & Kolding, J. (2021). Anchovy powder enrichment in brown rice?based instant cereal: a process optimization study using Response Surface Methodology (RSM). Food Science & Nutrition, 9 (8), 4485-4497. Externer Link:http://dx.doi.org/10.1002/fsn3.2424
Desaulniers, D., Vasseur, Pkurz fürPhosphor., Jacobs, A., Aguila, M. C., Ertych, N. & Jacobs, M. N. (2021). Integration of Epigenetic Mechanisms into Non-Genotoxic Carcinogenicity Hazard Assessment: Focus on DNA Methylation and Histone Modifications. International Journal of Molecular Sciences, 22 (20), 10969. Externer Link:http://dx.doi.org/10.3390/ijms222010969
Graffunder, A. S., Paisdzior, S., Opitz, R., Renko, K., Kühnen, Pkurz fürPhosphor., & Biebermann, H. (2021). Design and Characterization of a Fluorescent Reporter Enabling Live-cell Monitoring of MCT8 Expression. Experimental and Clinical Endocrinology & Diabetes. Externer Link:https://doi.org/10.1055/a-1522-8535
Habedank, A., Kahnau, Pkurz fürPhosphor. & Lewejohann, L. (2021). Alternate without alternative: neither preference nor learning explains behaviour of C57BL/6J mice in the T-maze. Behaviour, 158 (7), 625-662. Externer Link:http://dx.doi.org/10.1163/1568539X-bja10085
Habedank, A., Urmersbach, B., Kahnau, Pkurz fürPhosphor., & Lewejohann, L. (2021). Okurz fürSauerstoff mouse, where art thou? The Mouse Position Surveillance System (MoPSS)-an RFID-based tracking system. Behavior Research Methods. Externer Link:https://doi.org/10.3758/s13428-021-01593-7
Hobbiesiefken, U., Mieske, Pkurz fürPhosphor., Lewejohann, L. & Diederich, K. (2021). Evaluation of different types of enrichment their usage and effect on home cage behavior in female mice. PLoS ONE, 16 (12), e0261876. Externer Link:http://dx.doi.org/10.1371/journal.pone.0261876
Hobbiesiefken, U., Urmersbach, B., Jaap, A., Diederich, K. & Lewejohann, L. (2021). Rating enrichment items by group-housed laboratory mice in multiple binary choice tests using an RFID-based tracking system. bioRxiv. Externer Link:http://dx.doi.org/10.1101/2021.10.20.465117
Kahnau, Pkurz fürPhosphor., Guenther, A., Boon, M. N., Terzenbach, J. D., Hanitzsch, E., Lewejohann, L. & Brust, V. (2021). Lifetime Observation of Cognition and Physiological Parameters in Male Mice. frontiers in Behavioral Neuroscience, 15, 709775. Externer Link:http://dx.doi.org/10.3389/fnbeh.2021.709775
Kerp, H., Renko, K., Hönes, G. S., Brix, K., Köhrle, J., Moeller, L. C., & Fuehrer, D. (2021). Age dependent response to T4 overtreatment and recovery on systemic and organ level. Journal of Molecular Endocrinology. Externer Link:https://doi.org/10.1530/JME-21-0109
Klutzny, S., Kornhuber, M., Morger, A., Schönfelder, G., Volkamer, A., Oelgeschläger, M. & Dunst, S. (2021). Quantitative high-throughput phenotypic screening for environmental estrogens using the E-Morph Screening Assay in combination with in silico predictions. Environment International, 158, 106947. Externer Link:http://dx.doi.org/10.1016/j.envint.2021.106947
Kornhuber, M., Dunst, S., Schönfelder, G., & Oelgeschläger, M. (2021). The E-Morph Assay: Identification and characterization of environmental chemicals with estrogenic activity based on quantitative changes in cell-cell contact organization of breast cancer cells. Environment International, 149, 106411. Externer Link:https://doi.org/10.1016/j.envint.2021.106411
Lana Yeganova, Dina Wiemann, Mariana Neves, Federica Vezzani, Amy Siu, Inigo Jauregi Unanue, Maite Oronoz, Nancy Mah, Aurélie Névéol, David Martinez, Rachel Bawden, Giorgio Maria Di Nunzio, Roland Roller, Philippe Thomas, Cristian Grozea, Olatz Perez-de-Viñaspre, Maika Vicente Navarro, and Antonio Jimeno Yepes. 2021. Externer Link:Findings of the WMT 2021 Biomedical Translation Shared Task: Summaries of Animal Experiments as New Test Set. In Proceedings of the Sixth Conference on Machine Translation, pages 664–683, Online. Association for Computational Linguistics
Likurz fürLithium, Y., Lee, H., Heo, W. D. & Zi, Z. (2021). Revisiting the Role of TGFβ Receptor Internalization for Smad Signaling: It is Not Required in Optogenetic TGFβ Signaling Systems. Advanced Biology, 5 (10), 2101008. Externer Link:http://dx.doi.org/10.1002/adbi.202101008
Lossow, K., Renko, K., Schwarz, M., Kopp, J. F., Schomburg, L., Schwerdtle, T. & Kipp, A. Pkurz fürPhosphor. (2021). The Nutritional Supply of Iodine and Selenium Affects Thyroid Hormone Axis Related Endpoints in Mice. Nutrients, 13 (11), 3773. Externer Link:http://dx.doi.org/10.3390/nu13113773
Marx-Stoelting, Pkurz fürPhosphor., Solano, M.L.R., Aoyama, H., Adams R.H., Bal-Price A.,, Buschmann, J., Chahoud, I., Clark, R., Fang, T., Fujiwara, M., Gelinsky, M., Grote, K., Horimoto, M., Bennekou, S.H., Kellner, R., Kuwagata, M., Leist, M., Lang, A., Likurz fürLithium, W., Mantovani, A., Makris, S.L., Paumgartten, F., Perron, M., Sachana, M., Schmitt, A., Schneider, S., Schönfelder,. G, Schulze, F., Shiota, K., Solecki, R. (2021). 25th anniversary of the Berlin workshop on developmental toxicology: DevTox database update, challenges in risk assessment of developmental neurotoxicity and alternative methodologies in bone development and growth. Reprod Toxicol, 100, 155-162. Externer Link:https://doi.org/10.1016/j.reprotox.2020.11.003
Mieske, Pkurz fürPhosphor., Diederich, K. & Lewejohann, L. (2021). Roaming in a Land of Milk and Honey: Life Trajectories and Metabolic Rate of Female Inbred Mice Living in a Semi Naturalisitc Environment. animals, 11 (10), 3002. Externer Link:http://dx.doi.org/10.3390/ani11103002
Neves, M., & Ševa, J. (2021). An extensive review of tools for manual annotation of documents. Briefings in Bioinformatics, 22(1), 146–163. Externer Link:https://doi.org/10.1093/bib/bbz130
Ohnesorge, N., Heinl, C., & Lewejohann, L. (2021). Current Methods to Investigate Nociception and Pain in Zebrafish. Frontiers in Neuroscience, 15, 632634. Externer Link:https://doi.org/10.3389/fnins.2021.632634
Olevska, A., Bert, B., Ebrahimi, L., Schönfelder, G., & Heinl, C. (2021). Ensuring Reproducible Research Requires a Support Infrastructure: The Value of Public Registries to Publishers. Science Editor, 4–7. Externer Link:https://doi.org/10.36591/SE-D-4401-4
Schmerbeck, S., Schulze, F., Scheinpflug, J., Ebrahimi, L. (2021). Organ-on-chip systems and the 3Rs. Science in School, 54, 1-4. Externer Link:https://www.scienceinschool.org/article/2021/organ-on-chip/
Schneider, M. R. (2021). Losing fat through the skin. Science (New York, N.Y.), 373(6554), 487–488. Externer Link:https://doi.org/10.1126/science.abg9079
Schneider, M. R., Oelgeschläger, M., Burgdorf, T., van Meer, Pkurz fürPhosphor., Theunissen, Pkurz fürPhosphor., Kienhuis, A. S., Persma. A. H., Vandebriel, R. J. (2021). Applicability of organ-on-chip systems in toxicology and pharmacology. Crit Rev Toxicol, 1-15. Externer Link:https://doi.org/10.1080/10408444.2021.1953439
Schönfelder, G., Oelgeschläger, M., Bischoff, Pkurz fürPhosphor., Kornhuber, M., Dunst, S. & Vogl, S. (2021). Screening Method for Estrogenic and Anti-Estrogenic Activity. Patent Application Publication. Externer Link:https://scholar.google.com/citations?view_op=view_citation&hl=de&user=vdN9E_oAAAAJ&sortby=pubdate&citation_for_view=vdN9E_oAAAAJ:5Ul4iDaHHb8C
Schwedhelm, Pkurz fürPhosphor., Kusnick, J., Heinl, C., Schönfelder, G., Bert, B. (2021). How many animals are used for SARS-CoV-2 research? EMBO reports, e53751. Externer Link: https://doi.org.10.15252/embr.202153751
Stevens, C., Hawkins, Pkurz fürPhosphor., Smulders, T. V., MacLellan, A., Lewejohann, L., Jirkof, Pkurz fürPhosphor., Boxall, J., Murphy, H., Moody, C. M., Turner, Pkurz fürPhosphor. V., Makowska, J. I. & Inman, C. (2021). Report of the 2020 RSPCA/UFAW rodent and rabbit welfare meeting. Animal Technology and Welfare. Externer Link:https://journal.atwjournal.com/atwapril2021#page=7
Sun, Q., Mehl, S., Renko, K., Seemann, Pkurz fürPhosphor., Görlich, C. L., Hackler, J., Minich, W. B., Kahaly, G. J. & Schomburg, L. (2021). Natural Autoimmunity to Selenoprotein Pkurz fürPhosphor Impairs Selenium Transport in Hashimoto's Thyroiditis. International Journal of Molecular Sciences, 22 (23), 13088. Externer Link:http://dx.doi.org/10.3390/ijms222313088
Tappe-Theodor, A., Pitzer, C., Lewejohann, L., Jirkof, Pkurz fürPhosphor., Siegeler, K., Segelcke, A., Drude, N., Pradier, B., Pogatzki-Zahn, E., Hollinderbäumer, B. & Segelcke, D. (2021). The "WWHow" concept for prospective categorization of post-operative severity assessment in rodents. ResearchGate. Externer Link:http://dx.doi.org/10.13140/RG.2.2.14852.86408
Tralau, T., Oelgeschläger, M., Kugler, J., Bloch, D., Braeuning, A., Burgdorf, T., Marx-Stoelting, Pkurz fürPhosphor., Ritz, V., Schmeisser, S., Trubiroha, A., Zellmer, S., Luch, A., Schönfelder, G., Solecki, R., & Hensel, A. (2021). A prospective whole-mixture approach to assess risk of the food and chemical exposome. Nature Food, 2(7), 463–468. Externer Link:https://doi.org/10.1038/s43016-021-00316-7
Van der Mierden, S., Leenaars, C. H. C., Boyle, E. C., Ripoli, F. L., Gass, Pkurz fürPhosphor., Durst, M., Goerlich-Jansson, V. C., Jirkof, Pkurz fürPhosphor., Keubler, L. M., Talbot, S. R., Habedank, A., Lewejohann, L., Tolba, R. H., & Bleich, A. (2021). Measuring endogenous corticosterone in laboratory mice - a mapping review, meta-analysis, and open source database. ALTEX, 38(1), 111–122. Externer Link:https://doi.org/10.14573/altex.2004221
Voß, A. L., Heuwieser, W., Mee, J. F. & Fischer-Tenhagen, C. (2021). Calving Management: A Questionnaire Survey of Veterinary Subject Matter Experts and Non-Experts. animals, 11 (11), 3129. Externer Link:http://dx.doi.org/10.3390/ani11113129
Wessels, L., Reich, F., Schmoger, S., Pucher, J., Atter, A., Käsbohrer, A., & Hammerl, J. A. (2021). Draft Genome Sequences of Pseudomonas sp. Isolates Recovered from Ghanaian Fish Food Samples in 2018. Microbiology Resource Announcements, 10(6). Externer Link:https://doi.org/10.1128/MRA.01332-20
Andresen, N., Wöllhaf, M., Hohlbaum, K., Lewejohann, L., Hellwich, Okurz fürSauerstoff., Thöne-Reineke, C., & Belik, V. (2020). Towards a fully automated surveillance of well-being status in laboratory mice using deep learning: Starting with facial expression analysis. PloS One, 15(4), e0228059. Externer Link:https://doi.org/10.1371/journal.pone.0228059
Ban, Z., Knöspel, F., & Schneider, M. R. (2020). Shedding light into the black box: Advances in in vitro systems for studying implantation. Developmental Biology, 463(1), 1–10. Externer Link:https://doi.org/10.1016/j.ydbio.2020.04.003
Bawden, R., Nunzio, G. D., Grozea, C., Unanue, I., Yepes, A., Mah, N., Martinez, D., Névéol, A., Neves, M., Oronoz, M., Viñaspre, Okurz fürSauerstoff. Pkurz fürPhosphor. de, Piccardi, M., Roller, R., Siu, A., Thomas, Pkurz fürPhosphor., Vezzani, F., Navarro, M., Wiemann, D., & Yeganova, L. (2020). Findings of the WMT 2020 Biomedical Translation Shared Task: Basque, Italian and Russian as New Additional Languages. 5th Conference on Machine Translation. Externer Link:https://hal.inria.fr/hal-02986356
Bischoff, Pkurz fürPhosphor., Kornhuber, M., Dunst, S., Zell, J., Fauler, B., Mielke, T., Taubenberger, A. V., Guck, J., Oelgeschläger, M., & Schönfelder, G. (2020). Estrogens Determine Adherens Junction Organization and E-Cadherin Clustering in Breast Cancer Cells via Amphiregulin. IScience, 23(11), 101683. Externer Link:https://doi.org/10.1016/j.isci.2020.101683
Burow, E., Grobbel, M., Tenhagen, B.-A., Simoneit, C., Szabó, I., Wendt, D., Kürbis, C., Ladwig-Wiegard, M., Banneke, S., & Käsbohrer, A. (2020). Antibiotic Resistance in Escherichia coli from Broiler Chickens After Amoxicillin Treatment in an Experimental Environment. Microbial Drug Resistance (Larchmont, N.Y.), 26(9), 1098–1107. Externer Link:https://doi.org/10.1089/mdr.2019.0442
Clayton, R. W., Langan, E. A., Ansell, D. M., de Vos, I. J. H. M., Göbel, K., Schneider, M. R., Picardo, M., Lim, X., van Steensel, M. A. M., & Paus, R. (2020). Neuroendocrinology and neurobiology of sebaceous glands. Biological Reviews of the Cambridge Philosophical Society, 95(3), 592–624. Externer Link:https://doi.org/10.1111/brv.12579
Heinl, C., Chmielewska, J., Olevska, A., Grune, B., Schönfelder, G., & Bert, B. (2020). Rethinking the incentive system in science: animal study registries: Preregistering experiments using animals could greatly improve transparency and reliability of biomedical studies and improve animal welfare. EMBO Reports, 21(1), e49709. Externer Link:https://doi.org/10.15252/embr.201949709
Jacobs, M. N., Colacci, A., Corvi, R., Vaccari, M., Aguila, M. C., Corvaro, M., Delrue, N., Desaulniers, D., Ertych, N., Jacobs, A., Luijten, M., Madia, F., Nishikawa, A., Ogawa, K., Ohmori, K., Paparella, M., Sharma, A. K., & Vasseur, Pkurz fürPhosphor. (2020). Chemical carcinogen safety testing: OECD expert group international consensus on the development of an integrated approach for the testing and assessment of chemical non-genotoxic carcinogens. Archives of Toxicology, 94(8), 2899–2923. Externer Link:https://doi.org/10.1007/s00204-020-02784-5
Kahnau, Pkurz fürPhosphor., Habedank, A., Diederich, K., & Lewejohann, L. (2020). Behavioral Methods for Severity Assessment. Animals, 10(7). Externer Link:https://doi.org/10.3390/ani10071136
Leenaars, C. H. C., van der Mierden, S., Durst, M., Goerlich-Jansson, V. C., Ripoli, F. L., Keubler, L. M., Talbot, S. R., Boyle, E., Habedank, A., Jirkof, Pkurz fürPhosphor., Lewejohann, L., Gass, Pkurz fürPhosphor., Tolba, R., & Bleich, A. (2020). Measurement of corticosterone in mice: a protocol for a mapping review. Laboratory Animals, 54(1), 26–32. Externer Link:https://doi.org/10.1177/0023677219868499
Lewejohann, L., Grune, B., Schönfelder, G., & Bert, B. (2020). Cut back on surplus laboratory animals. Nature, 578(7796), 515. Externer Link:https://doi.org/10.1038/d41586-020-00517-3
Lewejohann, L., Schwabe, K., Häger, C., & Jirkof, Pkurz fürPhosphor. (2020). Impulse for animal welfare outside the experiment. Laboratory Animals, 54(2), 150–158. Externer Link:https://doi.org/10.1177/0023677219891754
Mei, J., Kohler, J., Winter, Y., Spies, C., Endres, M., Banneke, S., & Emmrich, J. V. (2020). Automated radial 8-arm maze: A voluntary and stress-free behavior test to assess spatial learning and memory in mice. Behavioural Brain Research, 381, 112352. Externer Link:https://doi.org/10.1016/j.bbr.2019.112352
Ndikung, J., Storm, D., Violet, N., Kramer, A., Schönfelder, G., Ertych, N., & Oelgeschläger, M. (2020). Restoring circadian synchrony in vitro facilitates physiological responses to environmental chemicals. Environment International, 134, 105265. Externer Link:https://doi.org/10.1016/j.envint.2019.105265
Névéol, A., Jimeno Yepes, A., & Neves, M. L. (2020). MEDLINE as a parallel corpus: a survey to gain insight on French-, Spanish- and Portuguese-speaking authors’ abstract writing practice. In ELRA (Ed.), International Conference on Language Resources and Evaluation. Externer Link:https://hal.archives-ouvertes.fr/hal-03023950
Neves, M. (2020). Integration of the PubAnnotation ecosystem in the development of a web-based search tool for alternative methods. Genomics & Informatics, 18(2), e18. Externer Link:https://doi.org/10.5808/GI.2020.18.2.e18
Neves, M., & Seva, J. (2020). Annotationsaurus: A Searchable Directory of Annotation Tools. ArXiv:2010.06251 [Cs]. Externer Link:http://arxiv.org/abs/2010.06251
Rudeck, J., Vogl, S., Banneke, S., Schönfelder, G., & Lewejohann, L. (2020). Repeatability analysis improves the reliability of behavioral data. PloS One, 15(4), e0230900. Externer Link:https://doi.org/10.1371/journal.pone.0230900
Rudeck, J., Vogl, S., Heinl, C., Steinfath, M., Fritzwanker, S., Kliewer, A., Schulz, S., Schönfelder, G., & Bert, B. (2020). Analgesic treatment with buprenorphine should be adapted to the mouse strain. Pharmacology, Biochemistry, and Behavior, 191, 172877. Externer Link:https://doi.org/10.1016/j.pbb.2020.172877
Stolz, A., Becker, M., Wistorf, E., & Ertych, N. (2020). Biomedical Research Meets Toxicology: How In Vitro Chromosome Instability Methods Can Contribute to Carcinogenicity Prediction. Cancer Research, 80(8), 1626–1629. Externer Link:https://doi.org/10.1158/0008-5472.CAN-19-2822
van Jaarsveld, M. T. M., Deng, D., Ordoñez-Rueda, D., Paulsen, M., Wiemer, E. A. C., & Zi, Z. (2020). Cell-type-specific role of CHK2 in mediating DNA damage-induced G2 cell cycle arrest. Oncogenesis, 9(3), 35. Externer Link:https://doi.org/10.1038/s41389-020-0219-y
Weegh, N., Füner, J., Janke, Okurz fürSauerstoff., Winter, Y., Jung, C., Struve, B., Wassermann, L., Lewejohann, L., Bleich, A., & Häger, C. (2020). Wheel running behaviour in group-housed female mice indicates disturbed wellbeing due to DSS colitis. Laboratory Animals, 54(1), 63–72. Externer Link:https://doi.org/10.1177/0023677219879455
Wistorf, E., Knöspel, F., Schönfelder, G., & Schneider, M. R. (2020). 3R-related research funding: Insights from a meeting hosted by the German Centre for the Protection of Laboratory Animals (Bf3R). ALTEX, 37(2), 320–323. Externer Link:https://doi.org/10.14573/altex.2002201
Wittkowski, Pkurz fürPhosphor., Violet, N., Oelgeschläger, M., Schönfelder, G., & Vogl, S. (2020). A quantitative medium-throughput assay to measure Caenorhabditis elegans development and reproduction. STAR Protocols, 1(3), 100224. Externer Link:https://doi.org/10.1016/j.xpro.2020.100224
Zhang, X., Xu, Q., Zi, Z., Liu, Z., Wan, C., Crisman, L., Shen, J., & Liu, X. (2020). Programmable Extracellular Vesicles for Macromolecule Delivery and Genome Modifications. Developmental Cell, 55(6), 784-801.e9. Externer Link:https://doi.org/10.1016/j.devcel.2020.11.007
Zouboulis, C. C., Yoshida, G. J., Wu, Y., Xia, L., & Schneider, M. R. (2020). Sebaceous gland: Milestones of 30-year modelling research dedicated to the “brain of the skin”. Experimental Dermatology, 29(11), 1069–1079. Externer Link:https://doi.org/10.1111/exd.14184
Bawden, R., Bretonnel Cohen, K., Grozea, C., Jimeno Yepes, A., Kittner, M., Krallinger, M., Mah, N., Neveol, A., Neves, M., Soares, F., Siu, A., Verspoor, K., & Vicente Navarro, M. (2019). Findings of the WMT 2019 Biomedical Translation Shared Task: Evaluation for MEDLINE Abstracts and Biomedical Terminologies. Proceedings of the Fourth Conference on Machine Translation (Volume 3: Shared Task Papers, Day 2), 29–53. Externer Link:https://doi.org/10.18653/v1/W19-5403
Bert, B., Heinl, C., Chmielewska, J., Schwarz, F., Grune, B., Hensel, A., Greiner, M., & Schönfelder, G. (2019). Refining animal research: The Animal Study Registry. PLoS Biology, 17(10), e3000463. Externer Link:https://doi.org/10.1371/journal.pbio.3000463
Burgdorf, T., Piersma, A. H., Landsiedel, R., Clewell, R., Kleinstreuer, N., Oelgeschläger, M., Desprez, B., Kienhuis, A., Bos, Pkurz fürPhosphor., de Vries, R., de Wit, L., Seidle, T., Scheel, J., Schönfelder, G., van Benthem, J., Vinggaard, A. M., Eskes, C., & Ezendam, J. (2019). Workshop on the validation and regulatory acceptance of innovative 3R approaches in regulatory toxicology - Evolution versus revolution. Toxicology in Vitro, 59, 1–11. Externer Link:https://doi.org/10.1016/j.tiv.2019.03.039
Chmielewska, J., Bert, B., Grune, B., & Schönfelder, G. (2019). Rechtliche Aspekte der Anwendung des pharmakologisch wirksamen Stoffs Tamoxifen bei der konditionellen Genausschaltung im Versuchstier Maus. Natur Und Recht, 41(1), 26–32. Externer Link:https://doi.org/10.1007/s10357-018-3457-4
Dunst, S., & Tomancak, Pkurz fürPhosphor. (2019). Imaging Flies by Fluorescence Microscopy: Principles, Technologies, and Applications. Genetics, 211(1), 15–34. Externer Link:https://doi.org/10.1534/genetics.118.300227
Heberle, A. M., Razquin Navas, Pkurz fürPhosphor., Langelaar-Makkinje, M., Kasack, K., Sadik, A., Faessler, E., Hahn, U., Marx-Stoelting, Pkurz fürPhosphor., Opitz, C. A., Sers, C., Heiland, I., Schäuble, S., & Thedieck, K. (2019). The PI3K and MAPK/p38 pathways control stress granule assembly in a hierarchical manner. Life Science Alliance, 2(2). Externer Link:https://doi.org/10.26508/lsa.201800257
Jirkof, Pkurz fürPhosphor., Rudeck, J., & Lewejohann, L. (2019). Assessing Affective State in Laboratory Rodents to Promote Animal Welfare-What Is the Progress in Applied Refinement Research? Animals, 9(12). Externer Link:https://doi.org/10.3390/ani9121026
Kelly, L., Goeuriot, L., Suominen, H., Neves, M., Kanoulas, E., Spijker, R., Azzopardi, L., Likurz fürLithium, D., Jimmy, Palotti, J., & Zuccon, G. (2019). CLEF eHealth 2019 Evaluation Lab. In L. Azzopardi, B. Stein, N. Fuhr, Pkurz fürPhosphor. Mayr, C. Hauff, & D. Hiemstra (Eds.), Advances in Information Retrieval (pp. 267–274). Springer International Publishing. Externer Link:https://doi.org/10.1007/978-3-030-15719-7_36
Kelly, L., Suominen, H., Goeuriot, L., Neves, M., Kanoulas, E., Likurz fürLithium, D., Azzopardi, L., Spijker, R., Zuccon, G., Scells, H., & Palotti, J. (2019). Overview of the CLEF eHealth Evaluation Lab 2019. In F. Crestani, M. Braschler, J. Savoy, A. Rauber, H. Müller, D. E. Losada, G. Heinatz Bürki, L. Cappellato, & N. Ferro (Eds.), Experimental IR Meets Multilinguality, Multimodality, and Interaction (pp. 322–339). Springer International Publishing. Externer Link:https://doi.org/10.1007/978-3-030-28577-7_26
Knebel, C., Heise, T., Zanger, U. M., Lampen, A., Marx-Stoelting, Pkurz fürPhosphor., & Braeuning, A. (2019). The azole fungicide tebuconazole affects human CYP1A1 and CYP1A2 expression by an aryl hydrocarbon receptor-dependent pathway. Food and Chemical Toxicology, 123, 481–491. Externer Link:https://doi.org/10.1016/j.fct.2018.11.039
Knöspel, F., Ban, Z., Schönfelder, G., & Schneider, M. R. (2019). Next milestone in understanding early life-blastoids mimic embryogenesis in vitro. Biology of Reproduction, 100(1), 11–12. Externer Link:https://doi.org/10.1093/biolre/ioy182
Mei, J., Banneke, S., Lips, J., Kuffner, M. T. C., Hoffmann, C. J., Dirnagl, U., Endres, M., Harms, C., & Emmrich, J. V. (2019). Refining humane endpoints in mouse models of disease by systematic review and machine learning-based endpoint definition. ALTEX, 36(4), 555–571. Externer Link:https://doi.org/10.14573/altex.1812231
Neves, M., Butzke, D., & Grune, B. (2019). Evaluation of Scientific Elements for Text Similarity in Biomedical Publications. Proceedings of the 6th Workshop on Argument Mining, 124–135. Externer Link:https://doi.org/10.18653/v1/W19-4515
Schulze, F., Schneider, M.R. (2019). Externer Link:Hoffnung oder Humbug? Organ-on-a-chip in der biomedizinischen Forschung und als Alternative zum Tierversuch. Deutsches Tierärzteblatt, 67(10).
Solecki, R., Rauch, M., Gall, A., Buschmann, J., Kellner, R., Kucheryavenko, Okurz fürSauerstoff., Schmitt, A., Delrue, N., Likurz fürLithium, W., Hu, J., Fujiwara, M., Kuwagata, M., Mantovani, A., Makris, S.L., Paumgartten, F., Schönfelder, G., Schneider, S., Vogl, S., Kleinstreuer, N., Schneider, M., Schulze, F., Fritsche, E., Clark, R., Shiota, K., Chahoud, I. (2019) Update of the DevTox data database for harmonized risk assessment and alternative methodologies in developmental toxicology: Report of the 9th Berlin Workshop on Developmental Toxicity. Reprod Toxicol. 89, 124-129. Externer Link:https://doi.org/10.1016/j.reprotox.2019.07.003
Wittkowski, Pkurz fürPhosphor., Marx-Stoelting, Pkurz fürPhosphor., Violet, N., Fetz, V., Schwarz, F., Oelgeschläger, M., Schönfelder, G., & Vogl, S. (2019). Caenorhabditis elegans As a Promising Alternative Model for Environmental Chemical Mixture Effect Assessment-A Comparative Study. Environmental Science & Technology, 53(21), 12725–12733. Externer Link:https://doi.org/10.1021/acs.est.9b03266
Fetz, V., Stauber, R. H., & Knauer, S. K. (2018). Translocation Biosensors-Versatile Tools to Probe Protein Functions in Living Cells. Methods in Molecular Biology (Clifton, N.J.), 1683, 195–210. Externer Link:https://doi.org/10.1007/978-1-4939-7357-6_12
Hilse, K. E., Rupprecht, A., Egerbacher, M., Bardakji, S., Zimmermann, L., Wulczyn, A. E. M. S., & Pohl, E. E. (2018). The Expression of Uncoupling Protein 3 Coincides With the Fatty Acid Oxidation Type of Metabolism in Adult Murine Heart. Frontiers in Physiology, 9, 747. Externer Link:https://doi.org/10.3389/fphys.2018.00747
Knebel, C., Kebben, J., Eberini, I., Palazzolo, L., Hammer, H. S., Süssmuth, R. D., Heise, T., Hessel-Pras, S., Lampen, A., Braeuning, A., & Marx-Stoelting, Pkurz fürPhosphor. (2018). Propiconazole is an activator of AHR and causes concentration additive effects with an established AHR ligand. Archives of Toxicology, 92(12), 3471–3486. Externer Link:https://doi.org/10.1007/s00204-018-2321-x
Knebel, C., Neeb, J., Zahn, E., Schmidt, F., Carazo, A., Holas, Okurz fürSauerstoff., Pavek, Pkurz fürPhosphor., Püschel, G. Pkurz fürPhosphor., Zanger, U. M., Süssmuth, R., Lampen, A., Marx-Stoelting, Pkurz fürPhosphor., & Braeuning, A. (2018). Unexpected Effects of Propiconazole, Tebuconazole, and Their Mixture on the Receptors CAR and PXR in Human Liver Cells. Toxicological Sciences, 163(1), 170–181. Externer Link:https://doi.org/10.1093/toxsci/kfy026
Lang, A., Volkamer, A., Behm, L., Röblitz, S., Ehrig, R., Schneider, M., Geris, L., Wichard, J., & Buttgereit, F. (2018). In silico methods - Computational alternatives to animal testing. ALTEX, 35(1), 124–126. Externer Link:https://doi.org/10.14573/altex.1712031
Mei, J., Riedel, N., Grittner, U., Endres, M., Banneke, S., & Emmrich, J. V. (2018). Body temperature measurement in mice during acute illness: implantable temperature transponder versus surface infrared thermometry. Scientific Reports, 8(1), 3526. Externer Link:https://doi.org/10.1038/s41598-018-22020-6
Moussallem, D., Ferreira, T. C., Zampieri, M., Cavalcanti, M. C., Xexéo, G., Neves, M., & Ngomo, A.-C. N. (2018). RDF2PT: Generating Brazilian Portuguese Texts from RDF Data. Externer Link:https://arxiv.org/abs/1802.08150
Neves, M., Butzke, D., Schönfelder, G., & Grune, B. (2018). Bf3R at SemEval-2018 Task 7: Evaluating Two Relation Extraction Tools for Finding Semantic Relations in Biomedical Abstracts. Proceedings of The 12th International Workshop on Semantic Evaluation, 816–820. Externer Link:https://doi.org/10.18653/v1/S18-1130
Neves, M., Jimeno Yepes, A., Névéol, A., Grozea, C., Siu, A., Kittner, M., & Verspoor, K. (2018). Findings of the WMT 2018 Biomedical Translation Shared Task: Evaluation on Medline test sets. Proceedings of the Third Conference on Machine Translation: Shared Task Papers, 324–339. Externer Link:https://doi.org/10.18653/v1/W18-6403
Piersma, A. H., Burgdorf, T., Louekari, K., Desprez, B., Taalman, R., Landsiedel, R., Barroso, J., Rogiers, V., Eskes, C., Oelgeschläger, M., Whelan, M., Braeuning, A., Vinggaard, A. M., Kienhuis, A., van Benthem, J., & Ezendam, J. (2018). Workshop on acceleration of the validation and regulatory acceptance of alternative methods and implementation of testing strategies. Toxicology in Vitro, 50, 62–74. Externer Link:https://doi.org/10.1016/j.tiv.2018.02.018
Rudeck, J., Bert, B., Marx-Stoelting, Pkurz fürPhosphor., Schönfelder, G., & Vogl, S. (2018). Liver lobe and strain differences in the activity of murine cytochrome P450 enzymes. Toxicology, 404–405, 76–85. Externer Link:https://doi.org/10.1016/j.tox.2018.06.001
Salatzki, J., Foryst-Ludwig, A., Bentele, K., Blumrich, A., Smeir, E., Ban, Z., Brix, S., Grune, J., Beyhoff, N., Klopfleisch, R., Dunst, S., Surma, M. A., Klose, C., Rothe, M., Heinzel, F. R., Krannich, A., Kershaw, E. E., Beule, D., Schulze, Pkurz fürPhosphor. C., … Kintscher, U. (2018). Adipose tissue ATGL modifies the cardiac lipidome in pressure-overload-induced left ventricular failure. PLoS Genetics, 14(1), e1007171. Externer Link:https://doi.org/10.1371/journal.pgen.1007171
Scheinpflug, J., Pfeiffenberger, M., Damerau, A., Schwarz, F., Textor, M., Lang, A., & Schulze, F. (2018). Journey into Bone Models: A Review. Genes, 9(5). Externer Link:https://doi.org/10.3390/genes9050247
Schneider, M. R., & Pincelli, C. (2018). The 3R approach to experimental dermatology. Experimental Dermatology, 27(5), 441–442. Externer Link:https://doi.org/10.1111/exd.13673
Schneider, M. R., & Zouboulis, C. C. (2018). Primary sebocytes and sebaceous gland cell lines for studying sebaceous lipogenesis and sebaceous gland diseases. Experimental Dermatology, 27(5), 484–488. Externer Link:https://doi.org/10.1111/exd.13513
Steinfath, M., Vogl, S., Violet, N., Schwarz, F., Mielke, H., Selhorst, T., Greiner, M., & Schönfelder, G. (2018). Simple changes of individual studies can improve the reproducibility of the biomedical scientific process as a whole. PLOS ONE, 13(9), e0202762. Externer Link:https://doi.org/10.1371/journal.pone.0202762
Stolz, A., Schönfelder, G., & Schneider, M. R. (2018). Endocrine Disruptors: Adverse Health Effects Mediated by EGFR? Trends in Endocrinology and Metabolism: TEM, 29(2), 69–71. Externer Link:https://doi.org/10.1016/j.tem.2017.12.003
Bert, B., Dörendahl, A., Leich, N., Vietze, J., Steinfath, M., Chmielewska, J., Hensel, A., Grune, B., & Schönfelder, G. (2017). Rethinking 3R strategies: Digging deeper into AnimalTestInfo promotes transparency in in vivo biomedical research. PLoS Biology, 15(12), e2003217. Externer Link:https://doi.org/10.1371/journal.pbio.2003217
Burgdorf, T., Dunst, S., Ertych, N., Fetz, V., Violet, N., Vogl, S., Schönfelder, G., Schwarz, F., & Oelgeschläger, M. (2017). The AOP Concept: How Novel Technologies Can Support Development of Adverse Outcome Pathways. Applied In Vitro Toxicology, 3(3), 271–277. Externer Link:https://doi.org/10.1089/aivt.2017.0011
Chmielewska, J., Bert, B., Grune, B., Hensel, A., & Schönfelder, G. (2017a). Probleme aus der tierversuchsrechtlichen Praxis: Rechtliche Einordnung der Genotypisierungsmethoden sowie der Zucht immunmodifizierter Tiere. Natur Und Recht, 39(6), 385–392. Externer Link:https://doi.org/10.1007/s10357-017-3190-4
Chmielewska, J., Bert, B., Grune, B., Hensel, A., & Schönfelder, G. (2017b). Rechtliche Probleme der Betäubung von Versuchstieren. Natur Und Recht, 39(8), 538–544. Externer Link:https://doi.org/10.1007/s10357-017-3212-2
Dahlhoff, M., Gaborit, N., Bultmann, S., Leonhardt, H., Yarden, Y., & Schneider, M. R. (2017). CRISPR-assisted receptor deletion reveals distinct roles for ERBB2 and ERBB3 in skin keratinocytes. The FEBS Journal, 284(19), 3339–3349. Externer Link:https://doi.org/10.1111/febs.14196
Herold, S., Krämer, D., Violet, N., & King, R. (2017). Rapid process synthesis supported by a unified modular software framework. Engineering in Life Sciences, 17(11), 1202–1214. Externer Link:https://doi.org/10.1002/elsc.201600020
Kodzius, R., Schulze, F., Gao, X., & Schneider, M. R. (2017). Organ-on-Chip Technology: Current State and Future Developments. Genes, 8(10). Externer Link:https://doi.org/10.3390/genes8100266
Schulze, F., Gao, X., Virzonis, D., Damiati, S., Schneider, M. R., & Kodzius, R. (2017). Air Quality Effects on Human Health and Approaches for Its Assessment through Microfluidic Chips. Genes, 8(10). Externer Link:https://doi.org/10.3390/genes8100244
Weidner, C., Steinfath, M., Wistorf, E., Oelgeschläger, M., Schneider, M. R., & Schönfelder, G. (2017). A Protocol for Using Gene Set Enrichment Analysis to Identify the Appropriate Animal Model for Translational Research. Journal of Visualized Experiments, 126, 55768. Externer Link:https://doi.org/10.3791/55768
Bert, B., Chmielewska, J., Bergmann, S., Busch, M., Driever, W., Finger?Baier, K., Hößler, J., Köhler, A., Leich, N., Misgeld, T., Nöldner, T., Reiher, A., Schartl, M., Seebach?Sproedt, A., Thumberger, T., Schönfelder, G., & Grune, B. (2016). Considerations for a European animal welfare standard to evaluate adverse phenotypes in teleost fish. The EMBO Journal, 35(11), 1151–1154. Externer Link:https://doi.org/10.15252/embj.201694448
Bert, B., Chmielewska, J., Hensel, A., Grune, B., & Schönfelder, G. (2016). The animal experimentation quandary: stuck between legislation and scientific freedom: More research and engagement by scientists is needed to help to improve animal welfare without hampering biomedical research. EMBO Reports, 17(6), 790–792. Externer Link:https://doi.org/10.15252/embr.201642354
Jungnickel, H., Pund, R., Tentschert, J., Reichardt, Pkurz fürPhosphor., Laux, Pkurz fürPhosphor., Harbach, H., & Luch, A. (2016). Time-of-flight secondary ion mass spectrometry (ToF-SIMS)-based analysis and imaging of polyethylene microplastics formation during sea surf simulation. The Science of the Total Environment, 563–564, 261–266. Externer Link:https://doi.org/10.1016/j.scitotenv.2016.04.025
Kugler, J., Kemler, R., Luch, A., & Oelgeschläger, M. (2016). Editor’s Highlight: Identification and Characterization of Teratogenic Chemicals Using Embryonic Stem Cells Isolated From a Wnt/β-Catenin-Reporter Transgenic Mouse Line. Toxicological Sciences, 152(2), 382–394. Externer Link:https://doi.org/10.1093/toxsci/kfw094
Kugler, J., Luch, A., & Oelgeschläger, M. (2016). Transgenic Mouse Models Transferred into the Test Tube: New Perspectives for Developmental Toxicity Testing In Vitro? Trends in Pharmacological Sciences, 37(10), 822–830. Externer Link:https://doi.org/10.1016/j.tips.2016.06.009
Raasch, M., Rennert, K., Jahn, T., Gärtner, C., Schönfelder, G., Huber, Okurz fürSauerstoff., Seiler, A. E. M., & Mosig, A. S. (2016). An integrative microfluidically supported in vitro model of an endothelial barrier combined with cortical spheroids simulates effects of neuroinflammation in neocortex development. Biomicrofluidics, 10(4), 044102. Externer Link:https://doi.org/10.1063/1.4955184
Schlechtriem, C., Pucher, J., & Michalski, B. (2016). Dietary burden calculations relating to fish metabolism studies. Journal of the Science of Food and Agriculture, 96(5), 1415–1419. Externer Link:https://doi.org/10.1002/jsfa.7607
Weidner, C., Steinfath, M., Opitz, E., Oelgeschläger, M., & Schönfelder, G. (2016). Defining the optimal animal model for translational research using gene set enrichment analysis. EMBO Molecular Medicine, 8(8), 831–838. Externer Link:https://doi.org/10.15252/emmm.201506025
Chmielewska, J., Bert, B., Grune, B., Hensel, A., & Schönfelder, G. (2015). Der “vernünftige Grund” zur Tötung von überzähligen Tieren. Eine klassische Frage des Tierschutzrechts im Kontext der biomedizinischen Forschung. Natur Und Recht, 37(10), 677–682. Externer Link:https://doi.org/10.1007/s10357-015-2903-9
Riebeling, C., Fischer, K., Luch, A., & Seiler, A. E. M. (2015). Classification of reproductive toxicants with diverse mechanisms in the embryonic stem cell test. The Journal of Toxicological Sciences, 40(6), 809–815. Externer Link:https://doi.org/10.2131/jts.40.809
Schönfelder, G. (2015). Laboratory animals: German initiative opens up animal data. Nature, 519(7541), 33. Externer Link:https://doi.org/10.1038/519033d
Schönfelder, G., Grune, B., & Hensel, A. (2015). Animal welfare: Europe’s first “3Rs” governmental centre. Nature, 527(7576), 38. Externer Link:https://doi.org/10.1038/527038e
Smirnova, L., Seiler, A. E. M., & Luch, A. (2015). microRNA Profiling as Tool for Developmental Neurotoxicity Testing (DNT). Current Protocols in Toxicology, 64, 20.9.1-20.9.22. Externer Link:https://doi.org/10.1002/0471140856.tx2009s64